It contains a unique combination of ingredients – Urea, Ceramide and other Natural Moisturizing Factors (NMFs) – which bind moisture in and repair skin´s natural protective barrier to prevent further moisture loss. The formula has been clinically and dermatologically proven to deliver both immediate relief and intense, long-lasting moisturization for dry, rough hands, even after repeated hand-washing. It strengthens skin’s natural barrier, making skin resilient to dryness for up to 48 hours.